BDBM648229 US11884671, Example 6

SMILES Cc1cc2ncccc2cc1Nc1ncc2n(C)c(=O)n([C@H]3CC[C@H](O)CC3)c2n1

InChI Key InChIKey=WGZHCNCLATVGMN-WKILWMFISA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 648229   

TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Astrazeneca

US Patent
LigandPNGBDBM648229(US11884671, Example 6)
Affinity DataIC50: >1.00E+4nMAssay Description:JAK1: The 2×JAK/Tyr 06 (ThermoFisher Scientific proprietary) mixture was prepared in 50 mM HEPES pH 6.5, 0.01% BRIJ-35, 10 mM MgCl2, 1 mM EGTA, 0.02%...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent